D. Adhere to strict contraceptive measures while using the drug.Rationale: Tazarotene is highly teratogenic (can cause birth defects) even when used topically. Teach sexually active women of childbearing age using this drug to adhere to strict contraceptive measures. Lesions should not be dressed, and the drug should not be stopped without consulting the prescriber. Tazarotene does not alter the immune response and thus does not increase infection risk.