Question

Solve it: which insulin mutations may result in disease? mastering biology

Answer 1

Insulin mutations can result in diseases like type 1 diabetes, where there is a lack of insulin production. Injecting synthetic insulin can treat this condition.

Step-by-step explanation:

Insulin is a hormone that helps cells take up glucose from the blood. Mutations in the gene that codes for insulin can lead to diseases like type 1 diabetes. In type 1 diabetes, there is a mutation in the insulin gene that prevents the production of insulin, resulting in high blood glucose levels. This can be treated by injecting synthetic insulin into the body from outside sources.

Answer 2

The mutations may be a substitution, deletion, inversion, or addition. The mutations in insulin may alter its active sites responsible for receptor binding, or the time taken for the insulin to be degraded (half-life). Mutation on insulin may cause diseases such as hyperproinsulinemia or hyperinsulinemia.