Answer:
High-dose chemicals can damage DNA causing genotoxicity, which is defined as damage to DNA or genes. And this can be aggravated since many chemicals have had little toxicological evaluation.
Step-by-step explanation:
The cancers are caused by mutations in the DNA throughout the life of a person, in such a way that obeying the causative factors, in this case the chemicals, they leave a mutational pattern in the genome of each tumor. There is an interesting biomarker called TGx-DDI, which is based on some genes that are expressed in a cell subjected to the stress produced by the chemical compound. These genes reflect the way in which different pathways can provide information on how cells respond to the chemical.