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What do male calico cats, children with Down syndrome and children with Turner syndrome all have in common?
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What do male calico cats, children with Down syndrome and children with Turner syndrome all have in common?

User Pedro Faria
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they all have chromosome disorders (irregular number, extra or missing chromosomes)
User Mark Arnott
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Chromosome malfunction. Essentially, they all have a defect
User Sean Fausett
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