Using performance-enhancing drugs has various long-term effects that includes worsening acne, impotence, balding, stunt growth in adolescents, increased risk of blood clot and more serious effects such as heart and liver damage. When the liver is impaired, it can result to swelling of legs, arm and abdomen, worst case is jaundice. Meanwhile, damage heart will lead to increase risks of high blood pressure, heart attack and stroke.