There are many ways to do this depending on the property you have to use:
If you use the distributive property, you need to distribute 3/4 to -10 and 2/5. Distribute means you will multiply it so your resulting equation will be this:

Before you can add, you need to first make them like terms because you cannot add unlike fractions. Get the LCD and form your new equation:

Now you can just add them together to get:

and then simplify your fraction:

or -
The whole fraction becomes negative because when you divide integers and of them is negative, the final answer will be negative.