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During what trimester does cartilage begin to harden?

User Wecsam
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The embryonic cartilage begins to harden into bone at anytime around the 2nd trimester. The embryonic cartilage undergoes endochondral ossification wherein the chondrocytes is slowly replaced by osteocytes with subsequent deposition of calcium and hydroxyapatite; therefore converting the cartilages into bones.
User Kenji Noguchi
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