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The side chain of ________ has a pka in the physiological ph range and is therefore often involved in proton transfer during enzymatic catalysis.

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The answer to this question is histidine. Histidine is an α-amino acid involved in the biosynthesis of proteins. The structure of histidine includes an α-amino acid, a carboxylic acid group, and an imidazole side chain. Histidine was initially thought to be essential only for infants; however, it has since been found to be essential for adults too.
User Mattl
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