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Which of these exchanged between the old and new worlds caused the pilgrims to notice abandoned farms and food upon their arrival in 1620?

User Shaffe
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Disease was the number one killer of native peoples. They had had little exposure to the diseases of Europe. This led to some villages being almost completely wiped out and some tribes destroyed. 
User Architekt
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For Apex, "smallpox" is the answer

User Syex
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