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Activation of ionotropic receptors is most closely associated with:

User JaviAlgaba
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The answer is: generation of graded potential. Graded potentials are membrane potential of varying sizes in mV that are a result of opening up of ionotropic channels. When the graded potentials net value add up and reach the threshold potential, then an impulse is generated in the post synaptic neuron.
User Holtavolt
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