The correct answer is: Boston.
Lord North, prime minister from 1770 to 1782, is the author of this phrase, refering to the americans bad behavior. He said - ...you will never meet with proper obedience to the laws of this country until you habe destroyed that nest of locusts.- This was his reaction to the Boston Tea Party. On march 1774 he passed the Coercive acts and closed the port of Boston to all traffic.