Question

People that have a single allele (gene copy) for sickle cell anemia are typically not sick from the disease and are said to be carriers of sickle cell trait. these people will more often live in the malaria belt of sub-saharan africa. the most likely explanation for this is

Answer 1

This is simply that those with SCA can survive in Africa against. Their single gene copy gives them a protective advantage against being infected with malaria.