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When evaluating drugs to be used to treat a particular disease, which of these values is important in terms of determining the relative safety of the drug?

a.

XD-50 and LD-50

b.

LD-50 and TD-50

c.

ED-50 and LD-50

d.

TD-50 and ED-50

(Answer is D)

1 Answer

14 votes

Answer:

d. TD-50 and ED-50

Step-by-step explanation:

According to the United States National Library for Medicine, the Margin of safety for drugs is calculated using the formula TD-50 divided by ED-50

Where TD is the Toxic Dose while the ED is defined as the Effective Does or Does for Therapeutic response.

Hence, in this case, the correct answer is option D.

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