Question

Listen to me, and do not be afraid— for this disease infects no one but me. To what is “this disease” referring? the fact that Oedipus killed his father and married his mother Oedipus’s pride and anger leprosy, which was common at the time Oedipus’s blindness

Answer 1

The fact that Oedipus killed his father and married his mother........... Hope this helps :)  

Answer 2

The fact that Oedipus killed his father and married his mother.

Step-by-step explanation:

The "disease" that Oedipus refers to is the fact that he killed his father and married his mother. Oedipus did so accidentally, not knowing who the characters were, or how they were related. Nevertheless, when he finds out, he is horrified by his actions. He ends up taking his eyes out in penitence. This is where the concept of "Oedipus complex" comes from.