Question

Determine whether each cell is in the myeloid cell line or the lymphoid cell line.

Answer 1

The question involves differentiating cells from the myeloid and lymphoid lines, important in blood cell formation. Lymphoid stem cells lead to immunity-focused lymphocytes while myeloid stem cells are responsible for all other blood cells. Understanding these cell lines is essential for analyzing blood smears and the immune response.

Step-by-step explanation:

The student's question pertains to differentiating whether each cell is from the myeloid or lymphoid cell line, which is a key concept in hemopoiesis, the process of blood cell formation in the human body. Lymphoid stem cells give rise to lymphocytes, which include T cells, B cells, and natural killer (NK) cells. These cells are crucial for the immune system, with B cells maturing in the bone marrow and T cells maturing in the thymus. On the other hand, myeloid stem cells produce all other formed elements such as erythrocytes (red blood cells), megakaryocytes (which produce platelets), monocytes, and the granular leukocytes - neutrophils, eosinophils, and basophils. Both types of cells undergo several stages of development with various precursor stages often ending in '-blast', such as megakaryoblasts (precursors to megakaryocytes) and proerythroblasts (which develop into erythrocytes).

Answer 2

Attached is an image showing the lymphoid and myeloid cell lines.

From a multipotential hematopoietic stem cell, the myeloid stem cell and a lymphoid stem cell will arise.

The lymphoid stem cell will give rise to the lymphoblast and will give rise to either a natural killer cell (NK cell) or a lymphocyte. A lymphocyte will now go to either the thymus to produce T-lymphocytes or stay in the bone marrow to produce B-lymphocytes. B-lymphocytes may further differentiate to plasma cells (specialized antibody secreting cells).

The myeloid stem cell will give rise to other blood components and these include; (1) the megakaryoblast that will further differentiate to megakaryocyte and fragment into platelets; (2) the proerythroblast that will mature to a reticulocyte and then to mature red blood cells; (3) the myeloblast that will either differentiate into neutrophils, basophils, and eosinophils; and (4) monoblast that will mature to monocyte and will be activated in the presence of infection to a macrophage.