Question

A child with cystic fibrosis has an altered protein in his cells that stops chloride ions from leaving the cells. This protein most likely affects the function of ?

Answer 1

The right answer is chloride transport in cell membrane.

Cystic fibrosis is genetically translated by a mutation in the CFTR gene.

This gene encodes a transmembrane protein which is a chloride channel regulated by cAMP (cyclic Adenosine MonoPhosphate). This low-conductance channel is a regulator of other channels, particularly sodium channels such as the ENaC channel (Epithelial Na Channel) or the Outwardly Rectifying Chloride Channel (ORCC).

Answer 2

The altered protein affected the function of the cell membrane. The cell membrane which contain a bilayer control the movement of substance in and out of the cell and organelles. Due to this it is selective permeable to ion and organic molecules.