Answer: It was where the first shots of the Civil War were fired.
Explanation: Ft. Sumter is significant for being where the first shots of the Civil War were fired. Confederate forces began firing on the Union-held fort on April 12, 1861, at 4:30 a.m. and continued for 33 straight hours. No one died in the combat, though the war it caused would go down as the bloodiest in U.S. history.