Question

Which type of mutation results in abnormal amino acid sequence?

Answer 1

if a substitution changes the amino acid to a “stop,” it's called a NONSENSE mutation. frameshift, missense, silent or nonsense (hint: deletion or insertion will always be frameshift). Sickel cell anemia is the result of a type of mutation in the gene that codes for part of the hemoglobin molecule.

Answer 2

Frameshift, nonsense and missense

Step-by-step explanation:

The types of mutations that cause an abnormal amino acid sequence are: frameshift, nonsense and missense

The frameshift mutation occurs when, by insertion or loss of bases, the amino acid reading frame changes, because the sequence of bases has assumed an order different from the correct order. In translation the bases are read every three years, that is, each base triplet determines an amino acid. Thus, if the reading frame is changed, the way of grouping these three bases is changed and incorrect amino acids are inserted.

Nonsense mutation occurs when an entire codon (sequence of 3 bases) is changed, that is, there is a change of 3 bases, which will end up forming a wrong reading of amino acids that ends the translation, ending it prematurely.

In the missense mutation, the original codon is changed to a codon that encodes a different amino acid, causing, once again, a wrong reading of the amino acids.