Question

Which type of change would be more likely to have se­vere consequences—substitution or deletion? Why?

Answer 1

While both will equate changes in a genetic chain, deletion would have more severe consequences. A substitution mutation usually only causes minor disorders and diseases, like sickle cell anemia. Whereas deletion causes much more serious diseases, like cystic fibrosis, and turner syndrome which is where a female is born with only one X chromosome.