Final answer:
Without enzymes, a biological reaction would likely take much longer to occur or might not occur at all, due to high activation energies and less favorable cellular conditions.
Step-by-step explanation:
The most accurate description of how a biological reaction would change without enzymes is that the reaction would take significantly longer or stop completely. Enzymes are biological catalysts that dramatically increase the rate of biochemical reactions. Without enzymes, reactions may not proceed quickly enough to sustain life processes, given that cellular conditions are typically not conducive to quick reactions due to factors such as low body temperatures and low reactant concentrations.
Enzymes not only speed up these reactions but also lower the activation energy needed for the reactions to start. This essential role in lowering activation energy and speeding up reactions means that if an enzyme is not present or not functioning, a biochemical reaction that might otherwise happen in less than a second could take hours, days, or may not even occur at all. This highlights the vital importance of enzymes in maintaining the efficiency of biological systems.