Answer:
The Indian Wars of the early 18th century, combined with the increasing importation of African slaves, effectively ended the Native American slave trade by 1750. Colonists found that Native American slaves could easily escape, as they knew the country.
Step-by-step explanation:
Slavery replaced indentured servitude in the colonies in the 1660s because purchasing slaves became more economical for planters. Life expectancy in the Chesapeake and Southern colonies had increased, which meant that indentured servants were living long enough to fulfil their terms of indenture.