The right answer is A) Trisomy
Aberrant karyotypes containing an abnormal number of chromosomes are known in the human species. The best-known (and most common) chromosomal abnormality is trisomy 21, which is responsible for Down syndrome (mongolism). There are others such as Turner syndrome (woman with a single X chromosome) or Klinefelter syndrome (man XXY).
These abnormalities originate from the non-disjunction of the chromosomes of a pair of homologues during metaphase I of meiosis. At the end of division I, a daughter cell contains the two chromosomes of the pair considered and the other cell does not contain a chromosome of this pair. A similar result can be obtained during a bad distribution of chromatids during anaphase II.
After fertilization from a gamete of this type, a trisomy or a monosomy is obtained.