Final answer:
The Anti-Federalist argument that Samuel Bryan is making in the excerpt from The Anti-Federalist Papers is that a strong central government will become oppressive to the people and needs limitations, such as a Bill of Rights.
Step-by-step explanation:
In an excerpt from The Anti-Federalist Papers, Samuel Bryan, writing under the pseudonym 'Centinel,' makes the Anti-Federalist argument that a strong central government will become oppressive to the people and needs limitations, such as a Bill of Rights. Bryan argues that the powers granted to the general government by the Constitution are as complete as those of any state government and that the exercise of power should be restrained within proper limits.