Assuming you mean the binomial coefficients
n = (n !)/(r!(n - r)!)
10 = 10!/(4!× 6!) =(10 × 9 × 8 × 7)/(4 × 3 × 2 × 1) = = 210
4 = (4!)/(2! × 2!) = = 6
product = 210 × 6 = 1260
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= (n !)/(r!(n - r)!)
= 10!/(4!× 6!) =(10 × 9 × 8 × 7)/(4 × 3 × 2 × 1) = 
= 210
= (4!)/(2! × 2!) = 
= 6