So for this trinomial, I will be factoring by grouping. Firstly, what two terms have a product of 16x^2 and a sum of 10x? That would be 8x and 2x. Replace 10x with 2x + 8x:

Next, factor x^2 + 2x and 8x + 16 separately. Make sure that they have the same quantity inside the parentheses:

Now you can rewrite this as
, which is your final answer.