So, first step, find out how much more 2500000 is than 250000. 2500000 is 10 times more than 250000. Now, subtract 250000 from 2500000. That would give you 2250000. That is the difference of the two amounts of money. Now, to find how many hundred dollar bills. The amount we have now is 2250000. That is in 1-dollar bills. In order to make it into 100 dollar bills, we want to divide by 100. This will cause 2 zeroes to be taken off from 2250000, making the number 22500 hundred dollar bills.
Answer: There are 22500 more hundred-dollar bills in the 2.5 million dollar safe versus the 250 thousand dollar safe in hundred dollar bills.