Question

Many drugs are sold as their hydrochloric salts (r2nh2+cl−), formed by reaction of an amine (r2nh) with hcl. part 1 out of 4 draw the major organic product formed from the formation of acebutolol with hcl. acebutolol is a β blocker used to treat high blood pressure. omit any inorganic counterions.

Answer 1

Answer: -

Many drugs are sold as their hydrochloric salts (RNH₃⁺Cl⁻), formed by reaction of an amine (RNH₂) with HCl.

It is done because amines are generally liquids. But their hydrochloric salts are solid. A solid drug is always more preferable for drug companies as their handling and packaging are easier.

Acebutolol consists of one amide functionality as well as a secondary amine functionality.

When HCl is added, the lone pairs of the nitrogen of the secondary amine attacks it, leading to the formation of it's hydrochloric salts.