Answer:
Persistent plague was an important key role in pushing the empire, and weakening it . First appeared in the last years of Justinian's reign. It killed 10,000 people each day.
Step-by-step explanation:
The Byzantine Empire already had a lower population, devastating that empire. The reasons for the fall of the Byzantine Empire? 1) wide spread disease that killed many people . 2) The split of the Christian Church . 3) Invasions from Arab Muslims