Question

The solubility of acetanilide is 3.53 g in 100 ml of chloroform at 0 °c, and 29.1 g in 100 ml of chloroform at 60 °c. what is the maximum percent recovery that can be achieved for the recrystallization of acetanilide from chloroform?

Answer 1

The indication from which one can determine how much of active ingredient is recovered after purification method is said to be a percent recovery.

The formula for percent recovery is:

`Percent recovery = (weight of substance after crystallization)/(weight of substance used initialy)`

The solubility of acetanilide in 100 ml of chloroform at
`0^(o) C = 3.53 g`

The solubility of acetanilide in 100 ml of chloroform at
`60^(o) C = 29.1 g`

`weight of acetanilide after crystallization = 29.1 g - 3.53 g = 25.57 g`

`weight of acetanilide used initially = 29.1 g`

Substituting the values in the above formula:

`Percent recovery = (25.57)/(29.1)* 100`

`Percent recovery = 87.869` %.

Hence, the maximum percent recovery that can be achieved for the recrystallization of acetanilide from chloroform is
`87.869` %.