The majority of molecules comprises distinct kinds of protons or attached hydrogens. However, when functioning as acids, only the most acidic proton will take part in the acid-base reaction.
Acidic hydrogen refers to that hydrogen atom that is connected with two or more electronegative atoms, like oxygen, fluorine, and others, and can be dissociated into ions.
Acidic hydrogen signifies towards the hydrogen atom in an acid, which produces a positive ion when the acid dissociates. Thus, the acidic hydrogen in the non-cyclic AMP molecule will demonstrate an acidic characteristic on the molecule.