If you mean geographically/biologically - the world is changing, and so will the environment, and with the problems we have now a days, it's likely to change fast in aspects such as temperature (will get hotter), fauna and flora (will decrease), etc.
If you mean politically - some countries might gain more territory trough battles or wars, and some other countries might possible "reclaim" long-lost lands that belong to them historycally.
Hope it helped,
BioTeacher101