The answer is “Great and aggregate interests being referred to the national, the local and particular to the State legislatures”.
Federalist No. 10 is an essay composed by James Madison as the tenth of The Federalist Papers: a progression of papers started by Alexander Hamilton contending for the endorsement of the United States Constitution. Distributed on November 23, 1787 under the pen name", "Federalist No. 10 is among the most exceptionally respected of all American political compositions.
Madison saw the Constitution as framing a "happy combination" of a republic and a majority rules system and with the considerable and total interests being alluded to the national, the neighborhood and specific to the State lawmaking bodies the power would not be brought together, therefore making it more troublesome for unworthy contender to rehearse the horrible expressions by which races are over and over again conveyed.