Response:
Technologies and arms are optimistic, while pathogens are the negative influence of Europeans on America's future.
Explanation of:
The positive influence of Europeans on the future of the Americas was that they introduced technology, weapons, cattle, plants, etc. to America. They also also brought Christianity to the people of America. The detrimental effect of Europeans was the introduction of deadly diseases such as smallpox, syphilis and measles, etc., which destroyed a huge population of America due to lack of defense mechanisms, since these diseases were foreign to them.