the size of a Codon is 3 nucleotides.
The 20 amino acids are encoded by combinations of four nucleotides
If a codon were two nucleotides, the set of all combinations could only encode 16 amino acids.
since Codons are made up of three nucleotides, the set of all combinations can encode 64 amino acids. {i.e. 64 different combinations of four nucleotides taken three at a time.} But of the total of 64 codons, 61 encode amino acids and 3 specify termination of translation.
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