Answer;
-Kennedy's domestic agenda was an ambitious plan during a time of great change for the United States.
Step-by-step explanation;
-The statement that best describes President Kennedy’s domestic agenda is that Kennedy's domestic agenda was an ambitious plan during a time of great change for the United States.
-President Kennedy's domestic plan for the nation was called the New Frontier. President Kennedy started the New Frontier in 1961 and to a certain degree was a great success though its progress was cut short by his early death in 1963.
-The main objectives of the New Frontier were intended to improve the lives of the average American citizen though the program got off to a slow start it made huge developments in the standard of living of the common worker