To simplify this, the only thing we have to do is multiply all the quantities together. Since they are all connected by multiplication, it doesn't matter in which order we do it. Therefore, it might be helpful to multiply 4 and 5 first (because then we have a number with a zero at the end of it). 4 * 5 is 20. Now the expression is 20 * -3. 20 * 3 is 60, but 20 * -3 is -60 (because a positive number times a negative number is negative). That means that the answer is -60.