When there is a negative in the power sign, flip the place of the number:
1) If in numerator, flip to denominator
2) If in denominator, flip to numerator.
4^-5 = 1/(4^5)
4^-3 = 4^3
Multiply
4^3(1/(4^5)) = 4^3/4^5
Simplify:
(4 x 4 x 4)/(4 x 4 x 4 x 4 x 4) = 1/(4 x 4)
1/4² = 4^-2
F) 4^-2 is your answer
hope this helps