Point A lies on the x-axis and distance from point A to the y-axis is 2 units, then the coordinates of A are (-2,0) (-2, because A lies on the left side from the origin and 0 because A lies on x-axis).
The distances from point B to the x-axis and y-axis are 2 and 4, then tha coordinates of point B are (4,2).
To find the middle-point M of segment AB you should use formulas:

.
Then

.
Answer: M(1,1), correct choice is C.