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Change in the pH should (activate, deactivate, have no effect) the enzyme.
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Change in the pH should (activate, deactivate, have no effect) the enzyme.

User Akshaya Aradhya
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I would say it deactivates, because enzymes are picky about the type of environment they are in and will only work if they have the right environment. Hope i help. 
User Dcaswell
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