For this case we have the following equation:

To solve the problem, we must follow the following steps:
1) distributive property of 2 for x + 6 and 3 for x-4
2) Combine similar terms: variables with variables and constants with constants.
3) Clear the value of x.
Therefore, the first step is:
Distributive property.
Answer:
A reasonable first step that can be used to solve the equation is:
Distribute 2 to (x+6) and 3 to (x-4)