Question

Based on the information in the passage, pdk1 catalyzes the addition of phosphate to what functional group

Answer 1

Pdk1 catalyzes the addition of phosphate to specific amino acid residues in proteins through a process called protein phosphorylation, which is carried out by kinases. This can activate or turn off the function of the protein.

Step-by-step explanation:

pdk1 catalyzes the addition of phosphate to the amino acid residues serine, threonine, or tyrosine in proteins. This process is called protein phosphorylation and is carried out by enzymes called kinases. The addition of a phosphate group to these amino acid residues can result in a shape change in the protein, which can activate or turn off its function.

Answer 2

PDK1 (pyruvate dehydrogenase kinase 1) is an enzyme which inactivates the pyruvate dehydrogenase by phosphorylating it using an ATP molecule.

PDK1 (phosphoinositide-dependent protein kinase-1) acts by catalyzing the phosphorylation of Thr-229 (threonine at position 229 in pyruvate dehydrogenase).

This phosphorylation is synergistic with the phosphorylation of C-terminal Thr-389, but this one is not done by the PDK1.