In ancient times Rome was sacked by the Gauls in 390 B.C., the Visigoths in 410 A.D., the Vandals in 455 A.D, and the Ostrogoths in 546 A.D.
In medieval times Rome was sacked by the soldiers of the Norman from the duke of Apulia, Robert Guiscard in 1084and by the mutinous troops of the Holy Roman Emperor Charles V in 1527.