Question

Compared to normal glycogen the amount of what type of bond is decreased in lafora bodies

Answer 1

The correct answer is the glycosilic bond. Lafora disease is a neurodegenerative disease characterized by the presence of Lafora bodies in the cytosol. This disease causes impairment in the development of cerebral cortical neurons and it is a glycogen metabolism disorder. Lafora bodies are are aggregates of polyglucosans or abnormally shaped glycogen molecules ( abnormal chain lengths with higher phosphate levels).

Answer 2

Compared to normal glycogen, the type of bond that is decreased in Lafora bodies is Alpha 1-6 Glycosidic Bond.
Lafora normally functions as a phosphatase in normal people. If there is a mutation in the Lafora gene, there is an accumulation of covalently bound phosphates. Lafora bodes are glycogen polymers. The linkage of alpha 1-6 glycosidic bonds.