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Based on Chargaff's rule, the percentage of cytosine in the DNA of the bacterium S. lutea in Figure 12-3 should be around what?

The answer is 36.6%, but I don't know why. What's the reason why the answer is 36.6%?

Based on Chargaff's rule, the percentage of cytosine in the DNA of the bacterium S-example-1

1 Answer

4 votes
You have to remember Chargaff's rule which is pretty simple:
A always pairs with T; G always pairs with C
So look at your table.
Human: you know 2 numbers: G is 19.9 and T is 29.4. By Chargaff's rule you can fill in the other 2 so you'd have:
A (29.4), G (19.9), T (29.4), C (19.9)
I'll skip to the last one on the bacterium:
Here you only know one. But, you really know 2:
A is 13.4 so T must also be 13.4. This adds up to 26.8.
100-26.8= 73.2 (which is the amount of G+C); so divide this by 2 and you get 36.6 - so 36.6 G and 36.6 C!
Just remember who pairs with who...will never let you down!
User Ali ZahediGol
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