If your business operates in more than one state or in a large area, it's a good idea to register the trademark with what organization? C. USPTO. The UPSTO is the United States Patent and Trademark Office. Through this website, you are able to apply for a patient by filling out an application and filing it online. Once you've submitted your application you can check the status through their website. The same goes for a Trademark. When you want to apply for a trademark, you can file an application online through their website. When you are wanting to apply for trademark, you need to make sure you determine if a trademark is what you need or another form of Intellectual Property protection.