For this case we have the following expression:
(x ^ 2 + 2x + 1 / x ^ 2-8x + 16) / (x + 1 / x ^ 2-16)
Rewriting we have:
(((x + 1) (x + 1)) / ((x-4) (x-4))) / (x + 1 / ((x + 4) (x-4)))
Then, we cancel similar terms:
((x + 1) / (x-4)) / (1 / (x + 4))
Rewriting:
((x + 1) (x + 4)) / (x-4)
Answer:
((x + 1) (x + 4)) / (x-4)