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PLZZZZZZZ help find mRNA and A.A sequnce to this

Sickle cell hemoglobin DNA- cacgtggactgaggacacctc

Sickle cells hemglobin mRNA-

Sickle Cell shemoglobin A.A sequnce-

1 Answer

5 votes
DNA
cac gtg gac tga gga cac ctc

This gives rise to the mRNA which is exactly like your DNA (except no T - switch to U) - I like to spread them out in 3's (easier for me)

mRNA
CAC GUG GAC UGA GGA CAC CUC

You need to use a codon table to match these to the amino acid - I will put the 3 letter code right under the mRNA

CAC GUG GAC UGA GGA CAC CUC
HIS VAL ASP STOP GLY HIS LEU

Obviously this stop codon in the middle of the gene is a mutation...and a bad one as this hemoglobin molecule will not be properly made - which the issue in sickle cell anemia!
User Amica
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