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How does a chemist count the number of particles in a given number of moles of a substance?

User Terren
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The chemist the count the number of particles (Atoms, Molecules or Formula Unit) in a given number of moles of a substance by using following relationship.

Moles = # of Particles / 6.022 × 10²³

Or,

# of Particles = Moles × 6.022 × 10²³

So, from above relation it is found that 1 mole of any substance contains exactly 6.022 × 10²³ particles. Greater the number of moles greater will be the number of particles.
User Daniel Brose
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