Question

Some insecticides interfere with the removal of acetylcholine from the synaptic cleft. what effect will this have on muscle contraction

Answer 1

When insecticides interfere with the removal of acetylcholine from the synaptic cleft, it can lead to prolonged muscle contraction. This occurs because the insecticides inhibit the activity of the enzyme acetylcholinesterase, resulting in an accumulation of acetylcholine and continuous muscle stimulation.

Step-by-step explanation:

When some insecticides interfere with the removal of acetylcholine from the synaptic cleft, it can lead to prolonged muscle contraction. Normally, after acetylcholine transmits the nerve impulse across the synapse, the enzyme acetylcholinesterase breaks it down to prevent continuous stimulation of the muscle. However, these insecticides inhibit the activity of acetylcholinesterase, resulting in an accumulation of acetylcholine in the synaptic cleft, which then continues to stimulate the muscle. This can cause muscle spasms, twitching, and even paralysis.

Answer 2

The effect of insecticides will result in prolonged muscle contraction. Acetylcholinesterases are the enzymes that catalyze the breakdown of acetylcholine (Ach) in the synaptic cleft. This normally occurs, after the Ach achieves its effects on its receptors. On the other hand, acetylcholinesterase inhibitors inhibits the acetylcholinesterase enzyme thereby increasing the level and duration of action of the neurotransmitter ACh. Acetylcholinesterase inhibitors are used as insecticides.