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If two individuals that are heterozygous for the sickle cell allele (aa) mate with one another, what is the chance that their child will have sickle cell anemia ?
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If two individuals that are heterozygous for the sickle cell allele (aa) mate with one another, what is the chance that their child will have sickle cell anemia ?

User Nikunj Kakadiya
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1 Answer

6 votes
If you draw out the Punnet square you will see that you'd end up with:

25% AA (no disease, no carrier)
50% Aa (no disease, carrier)
25% aa (disease)


User Milson
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